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Article

Genome-wide association study for levels of total serum IgE identifies HLA-C in a Japanese population.

PloS one - 1 Jan 2013

Yatagai Yohei, Sakamoto Tohru, Masuko Hironori, Kaneko Yoshiko, Yamada Hideyasu, Iijima Hiroaki, Naito Takashi, Noguchi Emiko, Hirota Tomomitsu, Tamari Mayumi, Imoto Yoshimasa, Tokunaga Takahiro, Fujieda Shigeharu, Konno Satoshi, Nishimura Masaharu, Hizawa Nobuyuki

Abstract excerpt

Most of the previously reported loci for total immunoglobulin E (IgE) levels are related to Th2 cell-dependent pathways. We undertook a genome-wide association study (GWAS) to identify genetic loci responsible for IgE regulation. A total of 479,940 single nucleotide polymorphisms (SNPs) were test...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24324648
DOI: 10.1371/journal.pone.0080941
PMCID: PMC3851760

Genes

IFI16
LEMD2
PYHIN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24324648-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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