Article

Excessive immune responses in preterm placental villi compromise trophoblast health

2025-09-21

Abstract excerpt

Appropriate regulation of maternal immune cells in the pregnant uterus is essential for successful pregnancy, yet the impact of immune cells in placental villi (PV) on placental health remain understudied. We enriched immune cells from term and preterm PV for transcriptomic and functional analyses. Maternal and fetal immune cells were abundant, with maternal chimerism increasing at term. Fetal lymphocytes displaye...

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Literature Corpus work: d7e8ac2a-f3c7-5048-89d3-5954f1d572da
DOI: 10.1101/2025.09.20.677440

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