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Article

Subset scanning for multi-trait analysis using GWAS summary statistics.

Bioinformatics (Oxford, England) - 2 Jan 2024

Cao Rui, Olawsky Evan, McFowland Edward, Marcotte Erin, Spector Logan, Yang Tianzhong

Abstract excerpt

MOTIVATION: Multi-trait analysis has been shown to have greater statistical power than single-trait analysis. Most of the existing multi-trait analysis methods only work with a limited number of traits and usually prioritize high statistical power over identifying relevant traits, which heavily rely on domain knowledge. RESULTS: To handle diseases and traits with obscure etiology, we developed TraitScan, a...

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Identifiers

PMID: 38191683
DOI: 10.1093/bioinformatics/btad777
PMCID: PMC11087659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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