Article
IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population.
Scientific reports - 18 Apr 2018
Zha Ling-Feng, Nie Shao-Fang, Chen Qian-Wen, Liao Yu-Hua, Zhang Hong-Song, Dong Jiang-Tao, Xie Tian, Wang Fan, Tang Ting-Ting, Xia Ni, Xu Cheng-Qi, Zhou Ying-Chao, Zeng Zhi-Peng, Jiao Jiao, Wang Peng-Yun, Wang Qing K, Tu Xin, Cheng Xiang
Abstract excerpt
Interleukin-13 (IL-13) has important functions in atherosclerosis, but its role in coronary artery disease (CAD) is unclear. Here, we studied the genetic role of IL-13 in CAD in a Chinese Han population using tag SNPs covering the whole IL13 gene (i.e., rs1881457, rs2069744 and rs20541) and a two-stage cohort containing 1863 CAD cases and 1841 controls. Traditional risk factors for CAD, such as age, BMI, and...
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