Article
Relationship between chemokine (C-X-C motif) ligand 12 gene variant (rs1746048) and coronary heart disease: case-control study and meta-analysis.
Gene - 25 May 2013
Huang Yi, Zhou Jianqing, Ye Huadan, Xu Limin, Le Yanping, Yang Xi, Xu Weifeng, Huang Xiaoyan, Lian Jiangfang, Duan Shiwei
Abstract excerpt
The goal of our study is to evaluate the contribution of CXCL12 rs1746048 (hg19, chr10:44775574) to the risk of CHD in Han Chinese, and to summarize its role in CHD through meta-analysis of existing studies among various ethnic groups. Significant association is observed between rs1746048-C and an increased risk of CHD in Han Chinese (χ(2)=5.41, df=1, P=0.02). Post hoc analysis reveals an even stronger...
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