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Article

Rapidly Progressive Alzheimer's Disease: A Multicenter Update

18 Jun 2012

Abstract excerpt

The objective was to characterize a rapidly progressive subtype of Alzheimer's disease (rpAD). Multicenter (France, Germany, Japan, Spain) retrospective analyses of neuropathologically confirmed rpAD cases initially classified as prion disease due to their clinical phenotype were performed. Genetic properties, cerebrospinal fluid biomarkers, neuropathology, and clinical features were examined. Eighty-nine...

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PMID: 22460329
DOI: 10.3233/jad-2012-120007

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