Article
HLA class II polymorphisms as prognostic biomarkers for right and left-sided colon cancer.
The International journal of biological markers - 1 Mar 2024
Attia Amani, Lagha Awatef, Mezlini Amel, Ghazouani Ezzedine, Yacoubi-Loueslati Besma, Namouchi Imene
Abstract excerpt
BACKGROUND: Colon cancer (CC) is one of the most common malignancies worldwide. Characterization of new prognostic biomarkers for right-sided CC (RCC) and left-sided CC (LCC) may contribute to improving early detection. An association of human leukocyte antigens class II (HLA-II) with the predisposition to CC was suggested. AIM OF THE STUDY: We evaluated the association of DRB1 and DQB1 with the risk of LCC and...
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