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Article

Modeling of autism genetic variations in mice: focusing on synaptic and microcircuit dysfunctions.

Developmental neuroscience - 1 Jan 2012

Qiu Shenfeng, Aldinger Kimberly A, Levitt Pat

Abstract excerpt

Autism spectrum disorders (ASD) are heterogeneous neurodevelopmental disorders that are characterized by deficits in social interaction, verbal and nonverbal communication, and restrictive interests and repetitive behaviors. While human genetic studies have revealed marked heritability in ASD, it has been challenging to translate this genetic risk into a biological mechanism that influences brain development...

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PMID: 22572629
DOI: 10.1159/000336644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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