Article
Toll-like receptor 7 and tumor necrosis factor alpha polymorphisms in Egyptian patients with autoimmune thyroid diseases.
Journal of immunoassay & immunochemistry - 3 Mar 2024
Khalil Marwa Mohammed Ibrahim Mohammed, Monir Mansour Manal, Bakrey Hamed Ata Moustafa, Elaskary Shymaa Abdelsattar, Genena Shaimaa El Sayed Ramadan
Abstract excerpt
Hashimoto's thyroiditis (HT) and Graves' disease (GD) susceptibility depends on a complex interaction between environmental and genetic factors. Genes for tumor necrosis factor alpha (TNF-α) and toll-like receptors (TLRs) have been incorporated into the pathophysiology of autoimmune disorders. Our aim is to assess the association between TLR7 (rs179009) and TNF-α (rs1800629) polymorphisms and susceptibility to...
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