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Article

Polymorphisms in NLRP1 gene and susceptibility to autoimmune thyroid disease.

Autoimmunity - 1 May 2013

Alkhateeb Asem, Jarun Yousef, Tashtoush Reema

Abstract excerpt

The autoimmune thyroid disorders, or AITDs, comprise 2 related disorders, Graves' disease and Hashimoto thyroiditis. In AITD, immune system produces antibodies against autothyroid antigens. The etiology of AITDs involves a complex interaction between genetic predisposing factors and environmental triggering factors. Variations in NACHT leucine-rich repeat protein 1(NLRP1) gene a key regulator of the innate...

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Identifiers

PMID: 23374100
DOI: 10.3109/08916934.2013.768617

Genes

NLRP1

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