Article
Analysis of associations between the TLR3 SNPs rs3775291 and rs3775290 and COVID-19 in a cohort of professionals of Belém-PA, Brazil.
Frontiers in cellular and infection microbiology - 1 Jan 2023
Silva Marcos Jessé Abrahão, Vieira Marcelo Cleyton da Silva, Souza Alex Brito, Dos Santos Everaldina Cordeiro, Marcelino Beatriz Dos Reis, Casseb Samir Mansour Moraes, Lima Karla Valéria Batista, Lima Luana Nepomuceno Gondim Costa
Abstract excerpt
The objective of this article was to verify associations between the SNPs rs3775291 (Cytosine [C]>Thymine [T]) and rs3775290 (C>T) of TLR3 in professionals from Health Institutions (HI) who worked during the first pandemic wave and COVID-19. A case-control study was carried out with workers from HI in Belém-PA, Brazil, divided into symptomatology groups (Asymptomatic-AS, n=91; and Symptomatic-SI, n=121), and...
Topics
- Humans
- Polymorphism, Single Nucleotide
- Toll-Like Receptor 3
- Genetic Predisposition to Disease
- Case-Control Studies
- Brazil