Article
Association between IL-17A (rs2275913), IL-4 (rs2070874), NLRP3 (rs10754558) polymorphisms and COVID-19 in a cohort of professionals who worked in the first pandemic wave.
Human immunology - 1 May 2026
Silva Vieira Marcelo Cleyton da, Marcelino Beatriz Dos Reis, Abrahão Silva Marcos Jessé, Sardinha Daniele Melo, Sousa Bispo Sebastião Kauã de, Gondim Costa Lima Luana Nepomuceno, Batista Lima Karla Valéria
Abstract excerpt
INTRODUCTION: Host genetic polymorphisms in inflammatory mediators may influence COVID-19 clinical outcomes. This study investigated associations between IL-17A (rs2275913), IL-4 (rs2070874), and NLRP3 (rs10754558) polymorphisms and COVID-19 presentation in professionals exposed during the first pandemic wave in the Brazilian Amazon. METHODS: A total of 189 participants were classified as asymptomatic (AS) or...
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