Genetic variant in the AGT gene (rs699-GG) is associated with severe COVID-19 in Brazilian patients.

doi:10.1590/0001-3765202420240274

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Article

Genetic variant in the AGT gene (rs699-GG) is associated with severe COVID-19 in Brazilian patients.

Anais da Academia Brasileira de Ciencias - 1 Jan 2024

Farias Pablo C S, Cabral Leandro P, Neves Patrícia A F, Januário Caio A B, Cordeiro Beatriz M, Silva Júnior Wilson J DA, Baseggio Carolina, Paiva Júnior Sérgio S L, Araújo Paulo S R DE, Lorena Virgínia Maria B DE, Balbino Valdir Q, Lima Neto Reginaldo G

Abstract excerpt

The COVID-19 pandemic has been the largest pandemic of the past century, and various genetic factors have played a significant role in this context. This study aimed to analyze the frequency and association between specific SNPs rs3806268 (NLRP3), rs4925543 (NLRP3), rs12150220 (NLRP1), rs455060 (...

Topics

Humans
COVID-19
Polymorphism, Single Nucleotide

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Brazil

Male

Female

Middle Aged

SARS-CoV-2

Severity of Illness Index

Genetic Predisposition to Disease

Case-Control Studies

Adult

Genotype

Aged

Gene Frequency

Source

Open in PubMed

Identifiers

PMID: 39630802
DOI: 10.1590/0001-3765202420240274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-39630802-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.