Article
Genetic variant in the AGT gene (rs699-GG) is associated with severe COVID-19 in Brazilian patients.
Anais da Academia Brasileira de Ciencias - 1 Jan 2024
Farias Pablo C S, Cabral Leandro P, Neves Patrícia A F, Januário Caio A B, Cordeiro Beatriz M, Silva Júnior Wilson J DA, Baseggio Carolina, Paiva Júnior Sérgio S L, Araújo Paulo S R DE, Lorena Virgínia Maria B DE, Balbino Valdir Q, Lima Neto Reginaldo G
Abstract excerpt
The COVID-19 pandemic has been the largest pandemic of the past century, and various genetic factors have played a significant role in this context. This study aimed to analyze the frequency and association between specific SNPs rs3806268 (NLRP3), rs4925543 (NLRP3), rs12150220 (NLRP1), rs455060 (NLRC4), rs699 (AGT), (LEPR), and (MTHFR) and severe/critical outcomes in Brazilian patients with...
