Article
[Advance of research on Hereditary spastic paraplegia type 4].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Jan 2024
Wang Jie, Liu Yaxian, Zhang Lichun, Zhao Lirong, Liu Xiaoxia, Wang Xiaohua
Abstract excerpt
Spastic paraplegia type 4 (SPG4) is the most common type of autosomally inherited spastic paraplegia. Its main clinical features include typical simple hereditary spastic paraplegia, with neurological impairments limited to lower limb spasticity, hypertonic bladder dysfunction, and mild weakening of lower limb vibration sensation, without accompanying features such as nerve atrophy, ataxia, cognitive impairment,...
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