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Article

Allele-specific effect of various dietary fatty acids and ETS1 transcription factor on SCD1 expression.

Scientific reports - 2 Jan 2024

Tibori Kinga, Zámbó Veronika, Orosz Gabriella, Szelényi Péter, Sarnyai Farkas, Tamási Viola, Rónai Zsolt, Csala Miklós, Kereszturi Éva

Abstract excerpt

Overnutrition and genetic predisposition are major risk factors for various metabolic disorders. Stearoyl-CoA desaturase-1 (SCD1) plays a key role in these conditions by synthesizing unsaturated fatty acids (FAs), thereby promoting fat storage and alleviating lipotoxicity. Expression of SCD1 is influenced by various saturated and cis-unsaturated FAs, but the possible role of dietary trans FAs (TFAs) and SCD1...

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Identifiers

PMID: 38167845
DOI: 10.1038/s41598-023-50700-5
PMCID: PMC10761808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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