Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypoxia-induced galectin-8 maintains stemness in glioma stem cells via autophagy regulation

29 Dec 2023

Abstract excerpt

BACKGROUND: Glioma stem cells (GSCs) are the root cause of relapse and treatment resistance in glioblastoma (GBM). In GSCs, hypoxia in the microenvironment is known to facilitate the maintenance of stem cells, and evolutionally conserved autophagy regulates cell homeostasis to control cell population. The precise involvement of autophagy regulation in hypoxic conditions in maintaining the stemness of GSCs remains...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Galectins and Cancer Biology
Share to Glycosylation and Glycoproteins Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38158714
DOI: 10.1093/neuonc/noad264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypoxia-induced galectin-8 maintains stemness in glioma stem cells via autophagy regulationPMID 38158714Read ↗

The Autophagy Status of Cancer Stem Cells in Gliobastoma Multiforme: From Cancer Promotion to Therapeutic StrategiesSemantic proximity Read ↗

Autophagy in glioblastoma: A mechanistic perspectiveSemantic proximity Read ↗

The Role of Hypoxia and Cancer Stem Cells in Development of GlioblastomaSemantic proximity Read ↗

Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traitsSemantic proximity Read ↗

Glioblastoma Stem Cells at the Nexus of Tumor Heterogeneity, Immune Evasion, and Therapeutic ResistanceSemantic proximity Read ↗

Emerging Role of Glioma Stem Cells in Mechanisms of Therapy ResistanceSemantic proximity Read ↗

ASCL2 Maintains Stemness Phenotype through ATG9B and Sensitizes Gliomas to Autophagy Inhibitor.Semantic proximity Read ↗

Redox-Regulated Pathways in Glioblastoma Stem-like Cells: Mechanistic Insights and Therapeutic ImplicationsSemantic proximity Read ↗

Investigating the Association between the Autophagy Markers LC3B, SQSTM1/p62, and DRAM and Autophagy-Related Genes in GliomaSemantic proximity Read ↗

Hypoxia drives shared and distinct transcriptomic changes in two invasive glioma stem cell linesSemantic proximity Read ↗

Role of autophagy in regulation of glioma stem cells population during therapeutic stressSemantic proximity Read ↗

The STAT3-Regulated Autophagy Pathway in GlioblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.