Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Redox-Regulated Pathways in Glioblastoma Stem-like Cells: Mechanistic Insights and Therapeutic Implications

19 Aug 2025

Abstract excerpt

Glioblastoma (GBM) is the most aggressive primary brain tumor, characterized by rapid proliferation, invasiveness, therapeutic resistance, and an immunosuppressive tumor microenvironment. A subpopulation of glial stem-like cells (GSCs) within GBM tumors contributes significantly to tumor initiation, progression, and relapse, displaying remarkable adaptability to oxidative stress and metabolic reprogramming....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Genomics, phytochemicals, and oxidative stress
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40867215
DOI: 10.3390/brainsci15080884

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Redox-Regulated Pathways in Glioblastoma Stem-like Cells: Mechanistic Insights and Therapeutic ImplicationsPMID 40867215Read ↗

Oxidative Stress and Redox Imbalance: Common Mechanisms in Cancer Stem Cells and Neurodegenerative DiseasesSemantic proximity Read ↗

Glioblastoma Stem Cells at the Nexus of Tumor Heterogeneity, Immune Evasion, and Therapeutic ResistanceSemantic proximity Read ↗

Molecular Pathways and Genomic Landscape of Glioblastoma Stem Cells: Opportunities for Targeted TherapySemantic proximity Read ↗

Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma.Semantic proximity Read ↗

Redox regulation of cancer stem cells: Biology and therapeutic implicationsSemantic proximity Read ↗

Emerging Role of Glioma Stem Cells in Mechanisms of Therapy ResistanceSemantic proximity Read ↗

Unraveling the intricacies of glioblastoma progression and recurrence: insights into the role of NFYB and oxidative phosphorylation at the single-cell levelSemantic proximity Read ↗

Antioxidant network-based signatures cluster glioblastoma into distinct redox-resistant phenotypes.Semantic proximity Read ↗

The Glioblastoma Landscape: Hallmarks of Disease, Therapeutic Resistance, and Treatment OpportunitiesSemantic proximity Read ↗

The Strange Case of Jekyll and Hyde: Parallels Between Neural Stem Cells and Glioblastoma-Initiating CellsSemantic proximity Read ↗

Mechanisms of temozolomide resistance in glioblastoma - a comprehensive reviewSemantic proximity Read ↗

The Autophagy Status of Cancer Stem Cells in Gliobastoma Multiforme: From Cancer Promotion to Therapeutic StrategiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.