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Proteomic analysis reveals the aging-related pathways contribute to pulmonary fibrogenesis

22 Dec 2023

Abstract excerpt

Aging usually causes lung-function decline and susceptibility to chronic lung diseases, such as pulmonary fibrosis. However, how aging affects the lung-fibrosis pathways and leads to the occurrence of pulmonary fibrosis is not completely understood. Here, mass spectrometry-based proteomics was used to chart the lung proteome of young and old mice. Micro computed tomography imaging, RNA immunoprecipitation,...

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PMID: 38147026
DOI: 10.18632/aging.205355

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