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Article

Protein-centric omics integration analysis identifies candidate plasma proteins for multiple autoimmune diseases.

Human genetics - 1 Oct 2024

Chen Yingxuan, Liu Shuai, Gong Weiming, Guo Ping, Xue Fuzhong, Zhou Xiang, Wang Shukang, Yuan Zhongshang

Abstract excerpt

It remains challenging to translate the findings from genome-wide association studies (GWAS) of autoimmune diseases (AIDs) into interventional targets, presumably due to the lack of knowledge on how the GWAS risk variants contribute to AIDs. In addition, current immunomodulatory drugs for AIDs are broad in action rather than disease-specific. We performed a comprehensive protein-centric omics integration analysis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38143258
DOI: 10.1007/s00439-023-02627-0
PMCID: PMC11485194

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