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Article

Single-Nucleotide Polymorphisms of the PAR2 and IL-17A Genes Are Significantly Associated with Chronic Pain.

International journal of molecular sciences - 18 Dec 2023

Soeda Moe, Ohka Seii, Nishizawa Daisuke, Iseki Masako, Yamaguchi Keisuke, Arita Hideko, Hanaoka Kazuo, Kato Jitsu, Ogawa Setsuro, Hiranuma Ayako, Hasegawa Junko, Nakayama Kyoko, Ebata Yuko, Hayashida Masakazu, Ichinohe Tatsuya, Fukuda Ken-Ichi, Ikeda Kazutaka

Abstract excerpt

Patients with chronic pain are affected psychologically and socially. There are also individual differences in treatment efficacy. Insufficient research has been conducted on genetic polymorphisms that are related to individual differences in the susceptibility to chronic pain. Autoimmune disorders can lead to inflammation and chronic pain; therefore, we focused on the autoimmune-related protease-activated...

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Identifiers

PMID: 38139455
DOI: 10.3390/ijms242417627
PMCID: PMC10744199

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