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Article

Genome-wide association study identifies novel genetic variants associated with widespread pain in the UK Biobank (N = 172,230).

Molecular pain - 1 Jan 2025

Pan Qi, Cai Tengda, Tao Yiwen, Yang Luning, Compte Roger, Naeini Maryam Kazemi, Haque Mainul, Dottorini Tania, Williams Frances Mk, Meng Weihua

Abstract excerpt

OBJECTIVES: Widespread pain is a hallmark characteristic of fibromyalgia, commonly affecting older individuals. This study aimed to identify novel genetic variants associated with widespread pain by utilizing the extensive UK Biobank dataset. METHODS: We conducted a primary genome-wide association study (GWAS) using a novel definition of widespread pain, defined as pain experienced all over the body during the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 40509746
DOI: 10.1177/17448069251346603
PMCID: PMC12166267

Genes

ARHGEF28
LRMDA

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