Article
Multisite chronic pain and the risk of autoimmune diseases: A Mendelian randomization study.
Frontiers in immunology - 1 Jan 2023
Tang Yidan, Liu Weizhi, Kong Weishuang, Zhang Shuangyi, Zhu Tao
Abstract excerpt
Background: Accumulating evidence has demonstrated that an association between chronic pain and autoimmune diseases (AIDs). Nevertheless, it is unclear whether these associations refer to a causal relationship. We used a two-sample Mendelian randomization (MR) method to determine the causal relationship between chronic pain and AIDs. Methods: We assessed genome-wide association study (GWAS) summary statistics for...
Topics
- Humans
- Diabetes Mellitus, Type 1
- Mendelian Randomization Analysis
- Genome-Wide Association Study
- Amyotrophic Lateral Sclerosis
- Chronic Pain
- Polymorphism, Single Nucleotide
- Arthritis, Rheumatoid
- Lupus Erythematosus, Systemic
- Multiple Sclerosis