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Article

Systematic review and meta-analysis of genetic risk factors for neuropathic pain.

Pain - 1 May 2018

Veluchamy Abirami, Hébert Harry L, Meng Weihua, Palmer Colin N A, Smith Blair H

Abstract excerpt

Neuropathic pain (NP) is an increasingly common chronic pain state and a major health burden, affecting approximately 7% to 10% of the general population. Emerging evidence suggests that genetic factors could partially explain individual susceptibility to NP and the estimated heritability in twins is 37%. The aim of this study was to systematically review and summarize the studies in humans that have investigated...

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Source

Identifiers

PMID: 29351172
DOI: 10.1097/j.pain.0000000000001164

Genes

COMT
OPRM1
GCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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