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Article

Sialyltransferase Mutations Alter the Expression of Calcium-Binding Interneurons in Mice Neocortex, Hippocampus and Striatum.

International journal of molecular sciences - 7 Dec 2023

Blažetić Senka, Krajina Vinko, Labak Irena, Viljetić Barbara, Pavić Valentina, Ivić Vedrana, Balog Marta, Schnaar Ronald L, Heffer Marija

Abstract excerpt

Gangliosides are major glycans on vertebrate nerve cells, and their metabolic disruption results in congenital disorders with marked cognitive and motor deficits. The sialyltransferase gene St3gal2 is responsible for terminal sialylation of two prominent brain gangliosides in mammals, GD1a and GT1b. In this study, we analyzed the expression of calcium-binding interneurons in primary sensory (somatic, visual, and...

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Identifiers

PMID: 38139047
DOI: 10.3390/ijms242417218
PMCID: PMC10743413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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