Article
Sialyltransferase regulates nervous system function in Drosophila.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 5 May 2010
Repnikova Elena, Koles Kate, Nakamura Michiko, Pitts Jared, Li Haiwen, Ambavane Apoorva, Zoran Mark J, Panin Vladislav M
Abstract excerpt
In vertebrates, sialylated glycans participate in a wide range of biological processes and affect the development and function of the nervous system. While the complexity of glycosylation and the functional redundancy among sialyltransferases provide obstacles for revealing biological roles of sialylation in mammals, Drosophila possesses a sole vertebrate-type sialyltransferase, Drosophila sialyltransferase...
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