Article
BDNF variants, premorbid educational attainment, and disease characteristics in Alzheimer's disease: an exploratory study.
Journal of Alzheimer's disease : JAD - 1 Jan 2009
Zdanys Kristina F, Kleiman Timothy G, Zhang Huiping, Ozbay Fatih, MacAvoy Martha G, Gelernter Joel, van Dyck Christopher H
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that promotes neuronal survival, growth, and differentiation. The role of BDNF in learning and memory suggests that it may also modulate the clinical course of Alzheimer's disease (AD). This study aimed to determine whether BDNF genetic variants are related to premorbid educational attainment, progression of cognitive and functional decline, and...
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