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Article

Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Korthauer Laura E, Awe Elizabeth, Frahmand Marijam, Driscoll Ira

Abstract excerpt

Alzheimer's disease (AD) is characterized by memory loss and executive dysfunction, which correspond to structural changes to the medial temporal lobes (MTL) and prefrontal cortex (PFC), respectively. Given the overlap in cognitive deficits between healthy aging and the earliest stages of AD, early detection of AD remains a challenge. The goal of the present study was to study MTL- and PFC-dependent cognitive...

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Identifiers

PMID: 29865048
DOI: 10.3233/JAD-171043
PMCID: PMC7263481

Genes

APOE
BDNF
COMT
SORL1
TOMM40

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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