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Article

Genetics and functional imaging: effects of APOE, BDNF, COMT, and KIBRA in aging.

Neuropsychology review - 1 Mar 2015

Papenberg Goran, Salami Alireza, Persson Jonas, Lindenberger Ulman, Bäckman Lars

Abstract excerpt

Increasing evidence from cross-sectional and longitudinal molecular-genetic studies suggests that effects of common genetic variations on cognitive functioning increase with aging. We review the influence of candidate genes on brain functioning in old age, focusing on four genetic variations that have been extensively investigated: APOE, BDNF, COMT, and KIBRA. Similar to the behavioral evidence, there are reports...

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Source

Identifiers

PMID: 25666727
DOI: 10.1007/s11065-015-9279-8

Genes

APOE
BDNF
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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