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Article

Association of Molecular Classification with FIGO Stage and Survival Outcomes in Endometrial Cancer.

Medicina (Kaunas, Lithuania) - 29 Apr 2026

Keskinkılıç Merve, Polat Gül, Bayramoğlu Zeynep, Aysal Ağalar Anıl, Bülbül Öztürk Göksenil, Ulukuş Emine Çağnur, Yavuzşen Tuğba, Öztop İlhan

Abstract excerpt

Background and Objectives: Molecular classification has emerged as a key determinant of prognosis in endometrial cancer and has recently been incorporated into the 2023 FIGO staging system. Tumors are categorized into four molecular subgroups-POLE-mutated (POLEmut), p53-abnormal (p53abn), mismatch repair-deficient (dMMR), and no specific molecular profile (NSMP)-each associated with distinct biological behavior...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42195099
DOI: 10.3390/medicina62050846
PMCID: PMC13208334

Genes

POLE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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