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Protective effects of IL18-105G > A and IL18-137C > Ggenetic variants on severity of COVID-19.

Cytokine - 1 Feb 2024

Tiemi Enokida Mori Mayara, Name Colado Simão Andréa, Danelli Tiago, Rangel Oliveira Sayonara, Luis Candido de Souza Cassela Pedro, Lerner Trigo Guilherme, Morais Cardoso Kauê, Mestre Tejo Alexandre, Naomi Tano Zuleica, Regina Delicato de Almeida Elaine, Maria Vissoci Reiche Edna, Maes Michael, Alysson Batisti Lozovoy Marcell

Abstract excerpt

OBJECTIVE AND DESIGN: A cross-sectional study evaluated the IL18-105G > A (rs360717) and IL18-137C > G (rs187238) variants on Coronavírus Disease 2019 (COVID-19) severity. SUBJECTS AND METHODS: 528 patients with COVID-19 classifed with mild (n = 157), moderate (n = 63) and critical (n = 308) disease were genotpyed for the IL18-105G > A and IL18-137C > G variants. RESULTS: We observed associations between severe +...

Topics

Humans
COVID-19
Cross-Sectional Studies
Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-18

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 38128426
DOI: 10.1016/j.cyto.2023.156476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-38128426-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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