Diagnostic and prognostic significance of IL-18 and its -607C/A polymorphism in COVID-19: Implications for CURB-65 severity scoring.

doi:10.1016/j.ric.2026.100034

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Diagnostic and prognostic significance of IL-18 and its -607C/A polymorphism in COVID-19: Implications for CURB-65 severity scoring.

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion - 1 Jan 2026

Rafeeq Dawan Dlshad, Othman Baghawan Ahmed, Kakoo Ashraf, Smail Shukur Wasman, Yashooa Raya Kh, Ghareeb Asmaa Ameen, Salih Rebaz Hamza, Janson Christer

Abstract excerpt

BACKGROUND: Interleukin-18 (IL-18) is a key inflammasome-related cytokine implicated in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. OBJECTIVE: This study investigated the diagnostic, prognostic, and immunogenetic relevance of IL-18 and its promoter polymorphism (-607C/A, rs1946518) in COVID-19 susceptibility, severity, and mortality among Kurdish coronavirus disease-2019 (COVID-19)...

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PMID: 41610796
DOI: 10.1016/j.ric.2026.100034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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