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Article

Interleukin-18 and COVID-19.

Epidemiology and infection - 16 Dec 2021

Schooling C M, Li M, Au Yeung S L

Abstract excerpt

Vulnerability to coronavirus disease (COVID)-19 varies due to differences in interferon gamma (IFNγ) immunity. We investigated whether a key modifiable interferon precursor, interleukin-18, was related to COVID-19, overall and by severity, using Mendelian randomisation. We used four established genome-wide significant genetic predictors of interleukin-18 applied to the most recent genome-wide association study of...

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Identifiers

PMID: 34911594
DOI: 10.1017/S0950268821002636
PMCID: PMC8755530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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