Article
A genetic variant in IL-6 lowering its expression is protective for critical patients with COVID-19.
Signal transduction and targeted therapy - 2 Apr 2022
Gong Bo, Huang Lulin, He Yongquan, Xie Wen, Yin Yi, Shi Yi, Xiao Jialing, Zhong Ling, Zhang Yi, Jiang Zhilin, Hao Fang, Zhou Yu, Li Huan, Jiang Li, Yang Xingxiang, Song Xiangrong, Kang Yan, Tuo Lin, Huang Yi, Shuai Ping, Liu Yuping, Zheng Fang, Yang Zhenglin
Abstract excerpt
Critical coronavirus disease 2019 (COVID-19) is associated with high mortality and potential genetic factors have been reported to be involved in the development of critical COVID-19. We performed a genome-wide association study to identify the genetic factors responsible for developing critical...
Topics
- COVID-19
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Interleukin-6
- Male
- Polymorphism, Single Nucleotide