Article
Computational insights into NIMA-related kinase 6: unraveling mutational effects on structure and function.
Molecular and cellular biochemistry - 1 Nov 2024
Panchal Nagesh Kishan, Mohanty Shruti, Prince Sabina Evan
Abstract excerpt
The NEK6 (NIMA-related kinase 6) serine/threonine kinase is a pivotal player in a multitude of cellular processes, including the regulation of the cell cycle and the response to DNA damage. Its significance extends to disease pathogenesis, as changes in NEK6 activity have been linked to the development of cancer. Non-synonymous single nucleotide polymorphisms (nsSNPs) in NEK6 have been linked to cancer as they...
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