Article
Effects of Tulp4 deficiency on murine embryonic development and adult phenotype.
Microscopy research and technique - 1 Apr 2024
Jäger Roland, Geyer Stefan H, Kavirayani Anoop, Kiss Máté G, Waltenberger Elisabeth, Rülicke Thomas, Binder Christoph J, Weninger Wolfgang J, Kralovics Robert
Abstract excerpt
Genetically engineered mouse models have the potential to unravel fundamental biological processes and provide mechanistic insights into the pathogenesis of human diseases. We have previously observed that germline genetic variation at the TULP4 locus influences clinical characteristics in patients with myeloproliferative neoplasms. To elucidate the role of TULP4 in pathological and physiological processes in...
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