Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells

18 Dec 2023

Abstract excerpt

A poor outcome for cholangiocarcinoma (CCA) patients is still a clinical challenge. CCA is typically recognized by the desmoplastic nature, which accounts for its malignancy. Among various extracellular matrix proteins, laminin is the most potent inducer for CCA migration. Herein, we accessed the expression profiles of laminin gene family and explored the significance of the key laminin subunit on CCA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38114514
DOI: 10.1038/s41598-023-48798-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cellsPMID 38114514Read ↗

PSMA3-AS1 induced by transcription factor PAX5 promotes cholangiocarcinoma proliferation, migration and invasion by sponging miR-376a-3p to up-regulate LAMC1Semantic proximity Read ↗

Laminin 332 expression levels predict clinical outcomes and chemotherapy response in patients with pancreatic adenocarcinomaSemantic proximity Read ↗

Overexpression of Laminin-5 Gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascadeSemantic proximity Read ↗

Molecular Mechanisms Driving Cholangiocarcinoma Invasiveness: An OverviewSemantic proximity Read ↗

Evaluation of the diagnostic ability of laminin gene family for pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Laminin isoforms in development and disease.Semantic proximity Read ↗

Matrix metalloproteinase-2 inducing COL1A1 synthesis via integrin alpha Ⅴ promotes invasion and metastasis of cholangiocarcinoma cellsSemantic proximity Read ↗

The correlation and role analysis of COL4A1 and COL4A2 in hepatocarcinogenesis.Semantic proximity Read ↗

Upregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma.Semantic proximity Read ↗

Multi-omics analysis of LAMB3 as a potential immunological and biomarker in pan-cancerSemantic proximity Read ↗

Overexpression of ECM1 Contributes to Migration and Invasion in Cholangiocarcinoma CellSemantic proximity Read ↗

LncRNA‐MEG3 inhibits cell proliferation and invasion by modulating Bmi1/RNF2 in cholangiocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.