Article
The correlation and role analysis of COL4A1 and COL4A2 in hepatocarcinogenesis.
Aging - 5 Jan 2020
Liu Yanli, Zhang Jiaye, Chen Yan, Sohel Hasan, Ke Xinrong, Chen Jingqi, Li Yin-Xiong
Abstract excerpt
Liver fibrosis biomarker, Type IV collagen, may function as hepatocarcinogenesis niche. However, among the six isoforms, the isoforms providing tumor microenvironment and their regulatory network are still unclarified. Based on bioinformatics analysis of hundreds of HCC transcriptome datasets from public databases, we found that COL4A1/2 expressions were significantly correlated with hepatocarcinogenesis,...
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