Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Matrix metalloproteinase-2 inducing COL1A1 synthesis via integrin alpha Ⅴ promotes invasion and metastasis of cholangiocarcinoma cells

19 Dec 2023

Abstract excerpt

INTRODUCTION AND OBJECTIVES: Cholangiocarcinoma (CCA) is characterized by early distant invasion and metastasis, whereas the underlying mechanism is still obscure. Increasing evidence shows that collagen type Ι alpha 1 (COL1A1) is a gene associated with the progression of multiple diseases. Here, we attempted to investigate the role of COL1A1 in CCA. MATERIALS AND METHODS: The expression of COL1A1 between tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Protease and Inhibitor Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38123132
DOI: 10.1016/j.aohep.2023.101279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Matrix metalloproteinase-2 inducing COL1A1 synthesis via integrin alpha Ⅴ promotes invasion and metastasis of cholangiocarcinoma cellsPMID 38123132Read ↗

Overexpression of ECM1 Contributes to Migration and Invasion in Cholangiocarcinoma CellSemantic proximity Read ↗

Collagen 1A1 (COL1A1) Is a Reliable Biomarker and Putative Therapeutic Target for Hepatocellular Carcinogenesis and MetastasisSemantic proximity Read ↗

lncRNA FLVCR1‑AS1 regulates cell proliferation, migration and invasion by sponging miR‑485‑5p in human cholangiocarcinomaSemantic proximity Read ↗

Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cellsSemantic proximity Read ↗

High expression of COL10A1 is associated with poor prognosis in colorectal cancerSemantic proximity Read ↗

Long Noncoding RNA AFAP1-AS1 Promoted Tumor Growth and Invasion in CholangiocarcinomaSemantic proximity Read ↗

Upregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma.Semantic proximity Read ↗

BAP1 acts as a tumor suppressor in intrahepatic cholangiocarcinoma by modulating the ERK1/2 and JNK/c-Jun pathwaysSemantic proximity Read ↗

Molecular Mechanisms Driving Cholangiocarcinoma Invasiveness: An OverviewSemantic proximity Read ↗

The correlation and role analysis of COL4A1 and COL4A2 in hepatocarcinogenesis.Semantic proximity Read ↗

Down-regulation of COL1A1 inhibits tumor-associated fibroblast activation and mediates matrix remodeling in the tumor microenvironment of breast cancerSemantic proximity Read ↗

Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.