Article
The association between phylogenetic lineage and the subclinical phenotype of pulmonary tuberculosis: A retrospective 2-cohort study.
The Journal of infection - 1 Feb 2024
Long Richard, Croxen Matthew, Lee Robyn, Doroshenko Alexander, Lau Angela, Asadi Leyla, Heffernan Courtney, Paulsen Catherine, Egedahl Mary Lou, Lloyd Colin, Li Vincent, Tyrrell Gregory
Abstract excerpt
BACKGROUND: Subclinical pulmonary tuberculosis (PTB) is an asymptomatic disease state between established TB infection and symptomatic (clinical) TB disease. It is present in 20-25% of PTB patients in high-income countries. Mycobacterium tuberculosis complex (MTBC) genetic heterogeneity, and differential host immunological responses, have been implicated in its pathogenesis. METHODS: To determine the association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
