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Effects of the Beijing genotype on latent tuberculosis infection, TB disease risk, and clustering of TB cases.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2024

Asare-Baah Michael, Séraphin Marie Nancy, Salmon-Trejo LaTweika A T, Johnston Lori, Dominique Lina, Ashkin David, Vaddiparti Krishna, Kwara Awewura, Maurelli Anthony T, Lauzardo Michael

Abstract excerpt

BACKGROUND: The Beijing genotype of Mycobacterium tuberculosis (Mtb) has sparked debate regarding its virulence and transmissibility. This study contributes to this discussion by assessing its effect on the risk of latent tuberculosis infection (LTBI), active tuberculosis (TB) disease among contacts, and clustering of known TB cases. METHODS: We conducted a retrospective cohort study using the records of 4457...

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Identifiers

PMID: 39059734
DOI: 10.1016/j.meegid.2024.105648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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