Article
Lessons from molecular epidemiology and comparative genomics.
Seminars in respiratory and critical care medicine - 1 Oct 2008
Mathema Barun, Kurepina Natalia, Fallows Dorothy, Kreiswirth Barry N
Abstract excerpt
Molecular biology has revolutionized the field of tuberculosis (TB) research. Comparative genomics and molecular epidemiology are providing revelations about the evolutionary origins of MYCOBACTERIUM TUBERCULOSIS and phylogenetic relationships between different strains and strain families. Accumulating evidence indicates that distinct strains of M. TUBERCULOSIS (genotype) may be associated with differential...
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