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Association of Toll-Like Receptor 7 (TLR7) Polymorphisms with Predisposition to Systemic Lupus Erythematosus (SLE): A Meta and Trial Sequential Analysis.

Biochemical genetics - 1 Oct 2024

Ranjan Shovit, Panda Aditya K

Abstract excerpt

Systemic Lupus Erythematosus (SLE) is an autoimmune disorder characterized by autoantibody production and organ involvement. The role of toll-like receptor-7 in SLE is well established. Although genetic variations in the TLR-7 gene have been associated with an increased risk of developing SLE, the findings are not consistent. We performed a meta-analysis of previously published articles on four important single...

Topics

Lupus Erythematosus, Systemic
Toll-Like Receptor 7
Humans
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38103124
DOI: 10.1007/s10528-023-10600-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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