Article
Association between Toll-Like Receptor 4 Polymorphisms and Systemic Lupus Erythematosus Susceptibility: A Meta-Analysis.
BioMed research international - 1 Jan 2016
Hu Weiping, Wu Senchao, Zhang Yanlin, Sigdel Keshav Raj, Lin Yong, Zhong Hongbin
Abstract excerpt
Family aggregation was observed among systemic lupus erythematosus (SLE) cases, suggesting the genetic factor may contribute to the susceptibility. Toll-like receptors (TLR) play key role in human immune system; in order to gain better insight on the association between TLR4 polymorphisms and SLE risk, a meta-analysis was conducted. In total 4 case-control studies have been included, involving 503 SLE cases and...
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