Association of CTLA-4 (+49 A/G) polymorphism with susceptibility to autoimmune diseases: A meta-analysis with trial sequential analysis.

doi:10.1016/j.intimp.2021.107617

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Article

Association of CTLA-4 (+49 A/G) polymorphism with susceptibility to autoimmune diseases: A meta-analysis with trial sequential analysis.

International immunopharmacology - 1 Jul 2021

Yu Lingxiang, Shao Ming, Zhou Tingting, Xie Huimin, Wang Feier, Kong Jiangping, Xu Shenqian, Shuai Zongwen, Pan Faming

Abstract excerpt

OBJECTIVES: In recent years, more and more studies have been focusing on the association between Cytotoxic T lymphocyte antigen-4 (CTLA-4) (+49 A/G) gene polymorphism and autoimmune diseases. However, the results of previous studies are still controversial. The meta-analysis is aiming at determining the association in CTLA-4 (+49 A/G) gene rs231775 polymorphism and ankylosing spondylitis (AS), rheumatoid...

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Identifiers

PMID: 33866246
DOI: 10.1016/j.intimp.2021.107617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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