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Article

Role of DLA-DRB1 amino acids outside the shared epitope in dachshund susceptibility to immune-mediated polyarthritis.

Veterinary immunology and immunopathology - 1 Jan 2024

Nakazawa Meg, Nakajima Ryuichi, Oshima Ayaka, Yamazaki Atsushi, Okano Masaharu, Miyamae Jiro, Katakura Fumihiko, Edamura Kazuya, Moritomo Tadaaki, Watari Toshihiro

Abstract excerpt

Canine immune-mediated polyarthritis (IMPA) is an idiopathic disorder encompassing both erosive and non-erosive forms of rheumatoid arthritis (RA), with a clinical picture similar to human RA. Resemblance in major histocompatibility complex (MHC)-associated risk between the two was first noted within the specific amino acid motif known as the shared epitope (SE) on human leukocyte antigen DRB1. Following further...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 38096644
DOI: 10.1016/j.vetimm.2023.110690

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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