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ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer

13 Dec 2023

Abstract excerpt

BACKGROUND: Colon cancer (CC) is a heterogeneous disease that is categorized into four Consensus Molecular Subtypes (CMS) according to gene expression. Patients with loco-regional CC (stages II/III) lack prognostic factors, making it essential to analyze new molecular markers that can delineate more aggressive tumors. Aberrant methylation of genes that are essential in crucial mechanisms such as epithelial...

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PMID: 38093305
DOI: 10.1186/s13148-023-01605-7

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