Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A molecular sub-cluster of colon cancer cells with low VDR expression is sensitive to chemotherapy, BRAF inhibitors and PI3K-mTOR inhibitors treatment

9 Oct 2019

Abstract excerpt

Gene expression based consensus molecular subtypes (CMS) and non-negative matrix factorization (NMF) sub-clusters are robust colon cancer classification systems. Although, the molecular features are clear, colon cancer subgroups based interventions are limited. To address this problem, we analyze the CMS and NMF subgroup guided drug sensitivity in colon cancer cell lines. CMS3 subtype cells are sensitive to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Colorectal Cancer Treatments and Studies
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31596728
DOI: 10.18632/aging.102349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A molecular sub-cluster of colon cancer cells with low VDR expression is sensitive to chemotherapy, BRAF inhibitors and PI3K-mTOR inhibitors treatmentPMID 31596728Read ↗

Comprehensive Analysis of Subtype-Specific Molecular Characteristics of Colon Cancer: Specific Genes, Driver Genes, Signaling Pathways, and Immunotherapy ResponsesSemantic proximity Read ↗

Identification of the clinical prediction model and biomarkers based on chromatin regulators in colon cancer by integrated analysis of bulk- and single-cell RNA sequencing dataSemantic proximity Read ↗

Traditional Chinese Medicine Syndromes Classification Associates with Tumor Cell and Microenvironment Heterogeneity in Colorectal Cancer: a Single Cell RNA Sequencing AnalysisSemantic proximity Read ↗

Traditional chinese medicine syndromes classification associates with tumor cell and microenvironment heterogeneity in colorectal cancer: a single cell RNA sequencing analysisSemantic proximity Read ↗

Explore the prognostic characteristics of immunogenic cell death-related genes in colon carcinoma based on multi-constraint canonical correlation analysis combined with multi-omicsSemantic proximity Read ↗

Development of molecular subtype specific prognostic marker signature in immune response associated colon cancer through fuzzy based transcriptomic approachSemantic proximity Read ↗

Classification of colon cancer patients into Consensus Molecular Subtypes using Support Vector MachinesSemantic proximity Read ↗

Multi-OMICs data analysis identifies molecular features correlating with tumor immunity in colon cancer.Semantic proximity Read ↗

Comparative analyses of the prognosis, tumor immune microenvironment, and drug treatment response between left-sided and right-sided colon cancer by integrating scRNA-seq and bulk RNA-seq dataSemantic proximity Read ↗

CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical modelsSemantic proximity Read ↗

Bi-clustering based biological and clinical characterization of colorectal cancer in complementary to CMS classificationSemantic proximity Read ↗

Analysis of multi-omics differences in left-side and right-side colon cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.