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Article

IGFBP3 methylation is a novel diagnostic and predictive biomarker in colorectal cancer.

PloS one - 1 Jan 2014

Perez-Carbonell Lucia, Balaguer Francesc, Toiyama Yuji, Egoavil Cecilia, Rojas Estefania, Guarinos Carla, Andreu Montserrat, Llor Xavier, Castells Antoni, Jover Rodrigo, Boland C Richard, Goel Ajay

Abstract excerpt

BACKGROUND AND AIM: Aberrant hypermethylation of cancer-related genes has emerged as a promising strategy for the development of diagnostic, prognostic and predictive biomarkers in human cancer, including colorectal cancer (CRC). The aim of this study was to perform a systematic and comprehensive analysis of a panel of CRC-specific genes as potential diagnostic, prognostic and predictive biomarkers in a large,...

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Source

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Identifiers

PMID: 25127039
DOI: 10.1371/journal.pone.0104285
PMCID: PMC4134211

Genes

IGFBP3
ALX4
GAS7
TWIST1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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