Article
Analysis of IL-1β, TGF-β, IL-5, ACE, PTPN22 gene polymorphisms, and gene expression levels in Turkish children with IgA vasculitis.
Molecular biology reports - 12 Dec 2023
Taşkın Raziye Burcu, Aydın İlyas, Aytaç Gülçin, Imamoglu Süleyman, Tunçay Secil Conkar, Bulut İpek Kaplan, Karaca Neslihan Edeer, Aksu Güzide, Berdeli Afig, Kütükçüler Necil
Abstract excerpt
OBJECTIVE: Immunoglobulin-A vasculitis (IgAV) is an inflammatory disease that affects small blood vessels. This study was performed to identify an association between protein tyrosine phosphatase non-receptor type 22 (PTPN22) + 788G > A (rs33996649), transforming growth factor-beta (TGF-β) -509C > T (rs18004069), interleukin 1-beta (IL-1β) -511C > T (rs16944), interleukin 5 (IL-5) -746C/T (rs2069812), and...
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