Article
Metabolic Program of Regulatory B Lymphocytes and Influence in the Control of Malignant and Autoimmune Situations.
Frontiers in immunology - 1 Jan 2021
Iperi Cristian, Bordron Anne, Dueymes Maryvonne, Pers Jacques-Olivier, Jamin Christophe
Abstract excerpt
Metabolic pathways have been studied for a while in eukaryotic cells. During glycolysis, glucose enters into the cells through the Glut1 transporter to be phosphorylated and metabolized generating ATP molecules. Immune cells can use additional pathways to adapt their energetic needs. The pentose phosphate pathway, the glutaminolysis, the fatty acid oxidation and the oxidative phosphorylation generate additional...
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